The Hellforge quest during Act 4 will always drop some runes, and it can be used as a reward to speed up the scenes D2R Ladder Items. The Countess's tomb, located in the lower part of the Forgotten Tower in Act 1's Black Marsh, is another great source of runes.Because they have a certain rarity moving from the most frequent (El) all the way to the most rare (Zod) typically, they're used to create the economy in Diablo 2.
El from Lem are generally considered low runes. Pul through Gul are generally considered to be mid runes, and Vex throughout Zod are typically considered to be high runes. If you spot the mid or high runs in your travels, make sure that you don't sell them easily!
Runewords are among the most powerful items you can build to craft in Diablo 2: Resurrected, though they do take quite time in order to complete. It is first necessary to locate the correct runes needed to craft the runeword. After that, you'll have to find the weapon or shield that can accept the runeword.
The item must be equipped with the correct number of open sockets to allow the runeword to work and the runes have to be put into the socketed item in the proper order Buy Diablo 2 Resurrected Items. The item must also be unadorned (white); magic (blue) rare (yellow) unique (gold) or set (green) items with enough sockets will not work for runewords.